Welcome to NoncoRNA
NoncoRNA: a database for experimentally supported
Non-Coding RNA and Drug Target associations in Cancer. Cancer is
an important cause of morbidity and mortality worldwide, in every
world region, and irrespective of the level of human development.
In addition, the incidence and mortality of cancer have increased
rapidly worldwide in recent years. The reasons are complex, but
drug resistance is the primary cause of clinical treatment
failure. However, the mechanism of drug resistant to
chemotherapeutic agents are not fully elucidated. Currently, more
and more evidences have been proved that non-coding RNAs play
critical roles in drug resistant. Whereas, the database
association with drug resistant are only little. In addition, the
information are incomprehensive.
To fill this gap, we have developed NoncoRNA, a manually
curated database of experimentally supported non-coding RNA and
drug target associations in cancer. The current version of
NoncoRNA contains 5,568 ncRNAs and 154 drugs in 134 cancers.
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The feather of NoncoRNA including
the following aspects:(1) The NoncoRNA is the first database
that contains multiple ncRNAs, such as lncRNA, miRNA, circRNA
and piRNA; (2) The NoncoRNA is the first database provides the
relationship between circRNA, piRNA and drug resistant in
cancer; (3) The NoncoRNA provides some relationship between
ncRNAs and drug resistant in cancer.
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better experience on NoncoRNA.
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